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Results 1 to 25 of 1179

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Genetic epidemiology of induced CYP3A4 activityRAHMIOGLU, Nilufer; HEATON, James; AHMADI, Kourosh R et al.Pharmacogenetics and genomics (Print). 2011, Vol 21, Num 10, pp 642-651, issn 1744-6872, 10 p.Article

The unique complexity of the CYP3A4 upstream region suggests a nongenetic explanation of its expression variabilityHUAN QIU; MATHÄS, Marianne; NESTLER, Sebastian et al.Pharmacogenetics and genomics (Print). 2010, Vol 20, Num 3, pp 167-178, issn 1744-6872, 12 p.Article

CYP3 phylogenomics : evidence for positive selection of CYP3A4 and CYP3A7HUAN QIU; TAUDIEN, Stefan; HERLYN, Holger et al.Pharmacogenetics and genomics (Print). 2008, Vol 18, Num 1, pp 53-66, issn 1744-6872, 14 p.Article

An amperometric biosensor with human CYP3A4 as a novel drug screening toolJOSEPH, Shiba; RUSLING, James F; LVOV, Yuri M et al.Biochemical pharmacology. 2003, Vol 65, Num 11, pp 1817-1826, issn 0006-2952, 10 p.Article

Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathwayKUN WANG; SHIYONG CHEN; WEN XIE et al.Biochemical pharmacology. 2008, Vol 75, Num 11, pp 2204-2213, issn 0006-2952, 10 p.Article

Evaluation of the effect of food and ketoconazole on the pharmacokinetics of the smoothened inhibitor PF-04449913 in healthy volunteersSHAIK, M. Naveed; LABADIE, Robert R; RUDIN, Dan et al.Cancer chemotherapy and pharmacology. 2014, Vol 74, Num 2, pp 411-418, issn 0344-5704, 8 p.Article

Semi-physiologically based pharmacokinetic modeling of paclitaxel metabolism and in silico-based study of the dynamic sensitivities in pathway kineticsFRANSSON, Martin N; BRUGARD, Jan; ARONSSON, Peter et al.European journal of pharmaceutical sciences. 2012, Vol 47, Num 4, pp 759-767, issn 0928-0987, 9 p.Article

Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in The Rotterdam StudyELENS, Laure; BECKER, Matthijs L; HAUFROID, Vincent et al.Pharmacogenetics and genomics (Print). 2011, Vol 21, Num 12, pp 861-866, issn 1744-6872, 6 p.Article

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinideNIEMI, M; BACKMAN, J. T; NEUVONEN, M et al.Diabetologia (Berlin). 2003, Vol 46, Num 3, pp 347-351, issn 0012-186X, 5 p.Article

Induction of CYP3As in HepG2 cells by several drugs. Association between induction of CYP3A4 and expression of glucocorticoid receptorUSUI, Tatsuhiro; SAITOH, Yukiya; KOMADA, Fusao et al.Biological & pharmaceutical bulletin. 2003, Vol 26, Num 4, pp 510-517, issn 0918-6158, 8 p.Article

Clobazam Therapeutic Drug Monitoring: A Comprehensive Review of the Literature With Proposals to Improve Future StudiesDE LEON, Jose; SPINA, Edoardo; DIAZ, Francisco J et al.Therapeutic drug monitoring. 2013, Vol 35, Num 1, pp 30-47, issn 0163-4356, 18 p.Article

Association of the CYP3A4*1B 5'-flanking region polymorphism with cyclosporine pharmacokinetics ir healthy subjectsMIN, David I; ELLINGROD, Vicki L.Therapeutic drug monitoring. 2003, Vol 25, Num 3, pp 305-309, issn 0163-4356, 5 p.Article

Molecular basis for rhythmic expression of CYP3A4 in serum-shocked HepG2 cellsTAKIGUCHI, Takako; TOMITA, Miho; MATSUNAGA, Naoya et al.Pharmacogenetics and genomics (Print). 2007, Vol 17, Num 12, pp 1047-1056, issn 1744-6872, 10 p.Article

Transcriptional induction of CYP3A4 by o,p'-DDT in HepG2 cellsMEDINA-DIAZ, Irma M; ELIZONDO, G.Toxicology letters. 2005, Vol 157, Num 1, pp 41-47, issn 0378-4274, 7 p.Article

CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12 : Evidence for an allelic variant with altered catalytic activitySATA, F; SAPONE, A; ELIZONDO, G et al.Clinical pharmacology and therapeutics. 2000, Vol 67, Num 1, pp 48-56, issn 0009-9236Article

Genetic signature consistent with selection against the CYP3A4*1B allele in non-African populationsSCHIRMER, Markus; TOLIAT, Mohammad R; HABERL, Michael et al.Pharmacogenetics and genomics (Print). 2006, Vol 16, Num 1, pp 59-71, issn 1744-6872, 13 p.Article

Activation of Pregnane X Receptor and Induction of MDR1 by Dietary PhytochemicalsSATSU, Hideo; HIURA, Yuto; MOCHIZUKI, Keiichi et al.Journal of agricultural and food chemistry (Print). 2008, Vol 56, Num 13, pp 5366-5373, issn 0021-8561, 8 p.Article

Studies on the interactions between drug and estrogen. II. On the inhibitory effect of 29 drugs reported to induce gynecomastia on the oxidation of estradiol at C-2 or C-17SATOH, Takashi; MUNAKATA, Haruka; FUJITA, Ken-Ichi et al.Biological & pharmaceutical bulletin. 2003, Vol 26, Num 5, pp 695-700, issn 0918-6158, 6 p.Article

Time-dependent inhibition of CYP3A4 by sertraline, a selective serotonin reuptake inhibitorMASUBUCHI, Yasuhiro; KAWAGUCHI, Yuki.Biopharmaceutics & drug disposition. 2013, Vol 34, Num 8, pp 423-430, issn 0142-2782, 8 p.Article

The prevalence of co-prescription of clinically relevant CYP enzyme inhibitor and substrate drugs in community-dwelling elderly AustraliansKERR, K. P; MATE, K. E; MAGIN, P. J et al.Journal of clinical pharmacy and therapeutics (Print). 2014, Vol 39, Num 4, pp 383-389, issn 0269-4727, 7 p.Article

CYP3A4/5 combined genotype analysis for predicting statin dose requirement for optimal lipid controlKITZMILLER, Joseph Paul; SULLIVAN, Danielle M; PHELPS, Mitchell A et al.Drug metabolism and drug interactions. 2013, Vol 28, Num 1, pp 59-63, issn 0792-5077, 5 p.Article

Contribution of CYP2C19 and CYP3A4 to the formation of the active nortilidine from the prodrug tilidineGRÜN, Barbara; MERKEL, Ulrike; RIEDEL, Klaus-Dieter et al.British journal of clinical pharmacology. 2012, Vol 74, Num 5, pp 854-863, issn 0306-5251, 10 p.Article

Prediction of the likelihood of drug interactions with kinase inhibitors based on in vitro and computational studiesWANG, Zhi-Xin; JIAZHI SUN; ZHOU, Shu-Feng et al.Fundamental & clinical pharmacology. 2014, Vol 28, Num 5, pp 551-582, issn 0767-3981, 32 p.Article

Genetic and environmental predictors of serum 25-hydroxyvitamin D concentrations among middle-aged and elderly Chinese in SingaporeROBIEN, Kim; BUTLER, Lesley M; RENWEI WANG et al.British journal of nutrition. 2013, Vol 109, Num 3, pp 493-502, issn 0007-1145, 10 p.Article

Association study of four activity SNPs of CYP3A4 with the precocious puberty in chinese girlsXIUJUAN XIN; XIAOHUI LUAN; JUNHUA XIAO et al.Neuroscience letters. 2005, Vol 381, Num 3, pp 284-288, issn 0304-3940, 5 p.Article

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